
Suicide is preventable and never inevitable. Regardless of this, greater than 720,000 individuals die by suicide yearly, and there are a lot of extra individuals who will make a suicide try of their lifetime (World Well being Organisation, 2024). It’s effectively established that suicide entails a fancy and dynamic interplay of organic, psychological, environmental, and socio-cultural elements (O’Connor, 2011). Nonetheless, a wealth of proof has demonstrated the robust affiliation between psychiatric problems, together with main depressive dysfunction, character problems and psychotic problems, and elevated danger of suicide amongst completely different populations (Baldessarini & Tondo, 2020; Bradvik, 2018).
Notably, mainstream suicidology, psychiatric and medical disciplines have sometimes theorised loss of life by suicide to be the tip results of psychiatric problems, or psychological diseases (Hjelmeland & Jaworski, 2019; White, 2017). Nonetheless, as Marsh (2016) asserts, these claims have typically been framed as ‘unassailable truths’ which have dominated views on suicide, and subsequently additionally suicide prevention efforts. Critically although, it has been argued that the complexity and socio-cultural formation of suicidality can’t be understood, or responded to, inside this angle (White, 2017). As such, you will need to emphasise that a person who has skilled suicidal misery, or survived a suicide try, could not have additionally skilled psychiatric problems or psychological sickness. This reality reminds us that discourses of danger, somewhat than an individual’s particular person lived experiences or wants, have typically framed our understanding of suicidal misery, thus limiting our responses to suicide prevention.
Within the present examine, Oquendo and colleagues (2024) aimed to handle the dearth of accessible proof on lifetime suicide makes an attempt amongst in any other case wholesome people, who had not met the factors for any psychiatric problems previous to their first try.

Is suicide merely the ‘finish outcome’ of psychological sickness or can it happen outdoors of psychological sickness?
Strategies
The researchers carried out secondary evaluation of present cross-sectional information utilizing the US Nationwide Epidemiological Examine of Addictions and Associated Situations III (NESARC-III), a nationally consultant population-based survey from 2012-2013. The general pattern was comprised of 36,309 individuals who have been aged between 20 and 65 years outdated. Amongst those that had skilled a lifetime suicide try, the intention was to estimate the share of individuals whose first suicide try occurred earlier than the onset of any psychiatric dysfunction. Information evaluation was carried out utilizing SAS, and the primary outcomes and measures have been:
- Demographics together with age group, intercourse, race and ethnicity
- Lifetime suicide try frequencies amongst general pattern (n=36,309)
- Among the many sub-sample (n=1948), who have been people who had skilled a lifetime suicide try, the self-reported presence or absence of a psychiatric dysfunction earlier than the primary lifetime suicide try
- Amongst sub-sample, separate analyses for intercourse variations (male/feminine), and age variations have been additionally carried out (20-34, 35-49, and 50-65 years)
Outcomes
From the general pattern of 36,309 individuals, 1948 people had skilled a number of suicide makes an attempt of their lifetime (5.2%; 95% CI, 4.8% to five.6%). From this sub-sample, 66.8% (95% CI, 64.1% to 69.4%) have been feminine, and 33.3% (95% CI, 30.6% to 35.9%) have been male. The overwhelming majority of those individuals have been White (70.9%), and the others have been Hispanic (14%), Black (9.8%), American Indian or Alaska Native (3.5%), and Asian, Native Hawaiian or Different Pacific Islander (1.8%).
Members with none psychiatric prognosis
The examine reported that 6.2% (95% CI, 4.9% to 7.4%) of individuals who had made a suicide try of their lifetime didn’t meet the factors for a lifetime psychiatric dysfunction on the time of the survey administration. Moreover, an estimated 13.4% (95% CI, 11.6% to fifteen.2%) of people had reported that their first suicide try occurred earlier than any psychiatric dysfunction onset. Due to this fact, an estimated complete of 19.6% respondents within the sub-sample had skilled a suicide try of their lifetime with out an antecedent psychiatric dysfunction.
Intercourse variations
Notably, there have been no important intercourse variations within the proportion of people with lifetime suicide makes an attempt who didn’t have a psychiatric dysfunction, nor in these reporting a lifetime suicide try earlier than the onset of any psychiatric dysfunction. Nonetheless, females (n=195) have been extra more likely to have made a suicide try throughout the identical 12 months because the onset of their first psychiatric dysfunction (14.9%; 95% CI, 12.5% to 17.3%) than males. Furthermore, males (n=410) have been extra more likely to have made a suicide try after the onset of a psychiatric dysfunction (70%; 95% CI, 65.2% to 74.9%) in comparison with females (60.3%; 95% CI, 56.9% to 63.7%).
Age variations
There have been no important variations throughout the three age teams in relation to the chance of reporting a lifetime suicide try with no psychiatric dysfunction, nor have been there any important variations within the onset of suicide makes an attempt throughout the lifespan relative to the onset of psychiatric diagnoses between the three specified age teams.

This analysis means that not all individuals who have made a suicide try of their lifetime have skilled psychiatric problems, or psychological sickness.
Conclusions
The authors conclude that:
These information counsel that suicide risk-reduction methods attending solely to people with psychiatric problems, even when these methods have been to lead to excellent detection and prevention, would miss about 20% of people that go on to try suicide.

Focussing suicide prevention efforts solely on those that have beforehand skilled a psychiatric dysfunction would miss round 20% of people that go on to try suicide.
Strengths and limitations
This cross-sectional examine offers us with vital and novel findings which reveal that not all individuals who make a suicide try of their lifetime can have skilled psychiatric problems, or psychological sickness, previous to their suicide try (19.6%). Though the examine analysed information from a considerable general pattern of 36,309 people, the sub-sample of those that had made a suicide try of their lifetime (n=1948) was comparatively small for a cross-sectional examine of this nature. Moreover, cross-sectional research have inherent limitations in relation to establishing trigger and impact, susceptibility of bias, and self-reporting bias the place individuals could misreport data. Furthermore, because the creator acknowledges, the NESARC-III survey doesn’t embrace all diagnoses akin to autism spectrum, obsessive-compulsive, and intermittent explosive problems that are related to elevated chance of suicide makes an attempt throughout ones’ lifetime (Hirvikoski et al., 2019; Pellegrini et al., 2020).
Given their findings, the authors go a way in the direction of suggesting that suicidal behaviour could not essentially be pathological. Nonetheless, additionally they assert that suicide makes an attempt could “manifest like different psychiatric problems, which are sometimes comorbid with one another” (p.576). Moreover, they advocate that suicidal behaviour be recorded as a separate psychiatric dysfunction, which might result in a uniform definition and a diagnostic code which might be helpful for clinicians. Though this suggestion has constructive implications for suicide danger screening, and thus suicide prevention, different students have challenged the notion that suicidal behaviour is inevitably pathological, and that it must be categorized as a psychiatric dysfunction (Hjelmeland & Jaworski, 2019; Marsh, 2016; White, 2017).

Whereas the big general pattern dimension strengthens the findings, limitations embrace a small sub-sample of suicide attempters, self-reporting bias, and excluded diagnoses, elevating vital questions on how we outline and handle suicidal habits
Implications for follow
The findings of this cross-sectional examine have important implications for medical follow, policymakers, future analysis, and suicide prevention insurance policies or methods. Oquendo and colleagues counsel {that a} historical past of suicidal behaviour or suicide makes an attempt must be recorded by clinicians, no matter whether or not a person has a psychiatric prognosis or not. That is significantly vital since a earlier historical past of suicidal behaviour has been proven to be related to an elevated chance of future makes an attempt, and loss of life by suicide. The authors additionally counsel that recording suicidal behaviour as a separate psychiatric dysfunction could result in a extra uniform definition and diagnostic code, which can show helpful for suicide prevention.
The present suicide danger discount methods aren’t detecting an estimated one-fifth of people who’ve skilled a suicide try of their lifetime. Consequently, suicide danger screening must be expanded past psychiatric populations and people who have a pre-existing psychological sickness prognosis. Clinicians and psychological well being professionals must be conscious that suicidal behaviour could manifest individually, or as comorbidities related to psychiatric problems or psychological sickness and may subsequently get hold of and document the historical past of a person’s experiences with suicidal behaviour, no matter whether or not the particular person has a pre-existing psychiatric dysfunction or not.
Well being and social care insurance policies ought to think about implementing broader screening protocols for suicide danger amongst completely different populations. It could be helpful for screening to happen at hospitals, physician surgical procedures, behavioural well being organisations, and different healthcare settings. Well being and social care insurance policies ought to think about implementing broader screening protocols for suicide danger amongst completely different populations. It could be helpful for screening to happen at hospitals, physician surgical procedures, behavioural well being organisations, and different healthcare settings.
There stays restricted analysis on suicide danger amongst populations that should not have a pre-existing psychiatric dysfunction or psychological sickness. Future analysis may discover the advanced elements which can be related to elevated chance of suicide try amongst this inhabitants, utilizing nationwide healthcare information. Utilizing nationwide healthcare information could enhance affected person security, enhance care and subsequently scale back suicide danger.

This analysis means that it might be useful to display everybody for earlier experiences of suicide, not simply these with present psychiatric diagnoses.
Assertion of pursuits
The creator has no competing pursuits to declare.
Hyperlinks
Major paper
Oquendo MA, Wall M, Wang S, Olfson M, Blanco C. Lifetime Suicide Makes an attempt in In any other case Psychiatrically Wholesome People. JAMA Psychiatry. 2024;81(6):572–578. doi:10.1001/jamapsychiatry.2023.5672
Different references
Baldessarini, R. J., & Tondo, L. (2020). Suicidal dangers in 12 DSM-5 psychiatric problems. Journal of affective problems, 271, 66-73.
Brådvikm, L. (2018). Suicide danger and psychological problems. Worldwide journal of environmental analysis and public well being, 15(9), 2018.
Hirvikoski, T., Boman, M., Chen, Q., D’Onofrio, B. M., Mittendorfer-Rutz, E., Lichtenstein, P., … & Larsson, H. (2020). Particular person danger and familial legal responsibility for suicide try and suicide in autism: a population-based examine. Psychological drugs, 50(9), 1463-1474.
Hjelmeland, H., Jaworski, Ok., Knizek, B., & Marsh, I. (2019). Problematic recommendation from suicide prevention specialists. Moral Human Psychology and Psychiatry, 20(2), 79-85.
Marsh, I. (2016). Critiquing Modern Suicidology. In J. White, I. Marsh, M. Kral, & J. Morris (Eds.), Crucial Suicidology—Reworking suicide analysis and prevention for the twenty first century (pp. 15–30). UBC Press.
Probert-Lindström, S., Bötschi, S., & Gysin-Maillart, A. (2024). The affect of therapy latency on suicide-specific therapy outcomes. Archives of suicide analysis, 28(3), 1009-1021.
Pellegrini, L., Maietti, E., Rucci, P., Casadei, G., Maina, G., Fineberg, N. A., & Albert, U. (2020). Suicide makes an attempt and suicidal ideation in sufferers with obsessive-compulsive dysfunction: A scientific overview and meta-analysis. Journal of affective problems, 276, 1001-1021.
White, J. (2017). What can important suicidology do? Demise Research, 41(8), 472–480. https://doi.org/10.1080/07481187.2017.1332901.
World Well being Organisation. (2024). Suicide. https://www.who.int/news-room/fact-sheets/element/suicide.